Santiago del Estero Province Vacations & Trips from $223

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Your Santiago del Estero Province Vacation

From start to finish, all the details are taken care of when you reserve a Santiago del Estero Province vacation package. So whether you're coming to experience its culture, or any of its other highlights, planning your adventure is easy. With so much to see on a trip to Santiago del Estero Province, it can be difficult to know where to begin. Kick off your journey in Santiago del Estero at Aguirre Park and Plaza Sarmiento — two much-loved attractions here. Another great city worth adding to your itinerary is Termas de Rio Hondo. Don't miss Tara Inti Natural Reserve and Rincon de Atacama Municipal Museum. Expedia has flights, hotels, car rentals and more to help you curate your own tailored Santiago del Estero Province vacation today.

Top destinations in Santiago del Estero Province

Santiago del Estero showing a pool, a hotel and a luxury hotel or resort
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Santiago del Estero

Santiago del Estero

The Latest Santiago del Estero Province Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Grand Hotel

Grand Hotel

3 out of 5
Price was $273, price is now $223 per person
$223
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Tucuman (TUC)
7.4/10 Good! (36 reviews)
Hotel del Jardín

Hotel del Jardín

4 out of 5
Save 100% on your flight
Price was $1,392, price is now $906 per person
$906
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Tucuman (TUC)
6/10 (1 review)
Hosteria Atahualpa Yupanqui

Hosteria Atahualpa Yupanqui

3 out of 5
Price was $327, price is now $244 per person
$244
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Tucuman (TUC)
8.8/10 Excellent! (16 reviews)
Gran Amérian Carlos V

Gran Amérian Carlos V

4 out of 5
Save 100% on your flight
Price was $561, price is now $421 per person
$421
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Tucuman (TUC)
9.2/10 Wonderful! (147 reviews)
Beautiful hotel, great decoration details, clean. Rooms are very confortable, clean, peaceful. Bathrooms in room have the thermal water , amazing bathtub. Great indoor - outdoor pool! Nice activities. The Spa is unique! Even you have a coach who guides you to enjoy the best from the "thermal circuit". Food really good and excellent night shows. They even went for me to the airport.

Reviewed on Jan 5, 2018

Hotel Emperatriz

Hotel Emperatriz

3.5 out of 5
Price was $284, price is now $258 per person
$258
per person
Apr 1 - Apr 4
found 1 day ago
Roundtrip flight included
Buenos Aires (BUE) to Tucuman (TUC)
9/10 Wonderful! (43 reviews)

Find the Best Santiago del Estero Province Vacation Packages

Santiago del Estero Province Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Vicecomodoro Angel de la Paz Aragones Airport (SDE)
Top Sights
Tara Inti Natural Reserve, Guemes Park and Aguirre Park

Santiago del Estero Province Hotel Deals

NH Santiago del Estero

NH Santiago del Estero

4 out of 5
Independencia 110 Santiago del Estero Santiago del Estero Province
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $71 total per night from Feb 7 to Feb 8
$71 total
Feb 7 - Feb 8
8.4/10 Very Good! (59 reviews)
I had an absolutely wonderful stay at the NH Santiago del Estero! From the moment I arrived, the staff went above and beyond to make me feel welcome. Their friendliness, professionalism, and attention to detail truly set this hotel apart. Whether it was the front desk assisting me or the restaurant ...

Reviewed on May 17, 2025

NH Santiago del Estero
Hilton Garden Inn Santiago del Estero

Hilton Garden Inn Santiago del Estero

3.5 out of 5
Leandro N Alem 148 Santiago del Estero
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $109 total per night from Jan 29 to Jan 30
$109 total
Jan 29 - Jan 30
9.6/10 Exceptional! (40 reviews)
The room was really nice and was prepared before our arrival. The AC running on a perfect temperature. I could perceive the room cleanness and overall details were double checked.

Reviewed on Jan 14, 2026

Hilton Garden Inn Santiago del Estero
Gran Amérian Carlos V

Gran Amérian Carlos V

4 out of 5
Avda Juan Bautista Alberdi 340 Termas de Rio Hondo Santiago del Estero
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (146 reviews)
Todo bien

Reviewed on Nov 10, 2025

Get rates
Gran Amérian Carlos V
See all 48 properties in Santiago del Estero Province
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Santiago del Estero Province vacation package cost?
Starting from as low as $223, you can create your own Santiago del Estero Province package. Simply bundle flights, hotels and car rentals and we'll reward you with discounts.
How do I get a cheap travel package to Santiago del Estero Province?
Browse and book everything in one place with our Santiago del Estero Province vacation packages. We have incredible bargains on flights, hotels, tours and more that'll keep your bank account happy and your adventurousness alive. And, with more than 550 air carriers and 1,000,000 hotel options throughout the world to pick from, there are endless opportunities to mix and match your own way.
What are the top hotels in Santiago del Estero Province?
When it comes to hotels in Termas de Rio Hondo, Hilton Garden Inn Santiago del Estero and Amérian Hotel Casino Carlos V are two excellent options. If you're also staying in Santiago del Estero, Selina Salta and Design Suites Salta will make you feel at home.
How far in advance should I book my Santiago del Estero Province vacation?
While not all air carriers advertise ticket prices early, it's usually possible to look up international flights on Expedia up to 12 months in advance. This is when you'll score some incredible deals. If you're booking at the last minute, you might still be in luck. Sometimes the lowest prices become available a few weeks before departure.
What does an Expedia Santiago del Estero Province travel package include?
Packages include hotels, rental cars and flights, but you can combine any of them to create your dream Santiago del Estero Province trip. You can also add on a few activities and experiences once you've made your booking. You're in control! When you combine your bookings with Expedia, you'll score discounts you won't find elsewhere.
What should I know before booking a Santiago del Estero Province travel package?
You can save a tidy sum by bundling your hotels, flights and rental cars. Once you've created your package, you can add on things like tours and activities. Your next awesome vacation is only a couple of clicks away.
Can I choose my airline with a Santiago del Estero Province Expedia vacation package?
You certainly can. Expedia has access to more than 550 airline partners all over the world, so fly with the carrier that's a good fit for your travel needs.
Does Expedia offer Book Now, Pay Later Santiago del Estero Province vacation packages?
With one of our vacation packages, you can customize both your trip and a payment arrangement. Expedia can help reduce financial burden relating to your travel with a Book Now, Pay Later solution, thanks to us working with online lender Affirm. That way, all you have to worry about is packing to jet off into the sunset.
If I'm not able to travel, can I cancel my Santiago del Estero Province vacation package?
It's difficult to predict what the future holds, so it's good to know that you can change or cancel your Santiago del Estero Province vacation package. If your booking was made in the last 24 hours, you may be eligible for a refund. If your booking is older, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Discover the most popular places to visit in Santiago del Estero Province

Gen. San Martin Artisan and Cultural Center

Commune with nature and explore the great outdoors at Gen. San Martin Artisan and Cultural Center during your travels in Termas de Rio Hondo. Amble around the area's parks or experience its museums.

Gen. San Martin Artisan and Cultural Center

Santo Domingo Convent

Santo Domingo Convent is just one of the places to see in Santiago del Estero, so why not enjoy the other things to explore during your travels? Make time to visit the spas and monuments while you're in the area.

Santo Domingo Convent

Santiago del Estero Cathedral

After visiting Santiago del Estero Cathedral, make a plan to see the other sights and activities in Santiago del Estero. Amble around the area's parks or experience its theater scene.

Santiago del Estero Cathedral
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.